Abuse Deterrent Technologies

We suggest that our technologies provide the following physico-chemical properties in order for our products to be considered abuse deterrent:

• Should be difficult to abuse through crushing, chewing or licking
• Release of opioid is likely to be slower or not instantaneous in a range of beverages and solvents
• Should not "dose dump", or instantaneously release the entire dose of opioid, in the presence of ethanol over a range of concentrations
• When pulverized and reduced to particles, should be difficult and time consuming to syringe or inject in the form and volume suitable for intravenous administration
• When pulverized or reduced to particles, contains an irritant which should make it difficult or inefficient to snort or inhale
• Release of opioid should be insignificant or inefficient via heating and vaporization
• Extraction of opioid which has been microwaved should be difficult or inefficient